Overview

Artificial intelligence is creating new capabilities for scientific research, from analysing complex datasets and supporting modelling and simulation to helping researchers design experiments and navigate scientific knowledge. But advances in AI capability do not translate automatically into scientific progress. Realising their value depends on how new tools become integrated into scientific practice, the capabilities of the institutions and communities adopting them, and the relationship between AI systems and human scientific judgement.

The Accelerate Programme for Scientific Discovery was established at the University of Cambridge in 2020 to support the use of machine learning and AI across the sciences. Led by Jessica Montgomery, the programme has provided a practical setting in which to explore how AI capabilities diffuse across disciplines and become useful in research. Its experience has informed a wider research agenda at ML@CL concerned with the conditions for effective and responsible adoption of AI in science.

This work examines AI adoption as a systems problem, shaped by the interaction of technical capability with scientific knowledge and practice, data and experimental infrastructure, engineering capacity, skills, incentives, and institutional arrangements. A central question is how new capabilities spread through the scientific system. Research arising from Accelerate has examined the importance of interdisciplinary communities, open research practices, reusable tools, and data stewardship in creating a ‘diffusion engine’ through which methods and knowledge can move between machine learning and scientific disciplines. This shifts attention from isolated demonstrations of AI capability towards the infrastructure and practices needed for widespread scientific use.

More recent work considers the integration of AI into scientific workflows and the consequences for scientific judgement and understanding. As AI systems become capable of undertaking larger parts of the research process, questions arise about which tasks can usefully be delegated, how outputs should be evaluated, where human expertise remains essential, and what it means for scientific knowledge to be produced through systems whose reasoning may not be accessible to researchers.

Together, this work asks a broader question: what needs to be true of the scientific system for advances in AI to translate into better science? Accelerate provides one empirical foundation for answering that question, connecting experience of AI adoption in scientific practice with wider ML@CL research on AI, institutions and technological change.

In the process, Accelerate Science trained over 2500 researchers in how to use AI in their science, and incubated over 50 new AI for science projects.

Recent Publications

Natural Language Processing markers in First Episode Psychosis and People at Clinical High-risk

Sarah E. Morgan, Kelly Diederen, Petra E. Vértes, Samantha H. Y. Ip, Bo Wang, Bethany Thompson, Arsime Demjaha, AndreaDe Micheli, Dominic Oliver, Maria Liakata, Paolo Fusar-Poli, Tom J. Spencer, Philip McGuire

Translational Psychiatry, 11(630):

Multimodal Graph Coarsening for Interpretable, MRI-Based Brain Graph Neural Network

Isaac Sebenius, Alexander Campbell, Sarah E. Morgan, Edward T. Bullmore, Pietro Liò

IEEE 31st International Workshop on Machine Learning for Signal Processing (MLSP), :

Deep learning for Bioimage Analysis in Developmental Biology

Adrien Hallou, Hannah G. Yevick, Bianca Dumitrascu, Virginie Uhlmann

Development, 148(18):

Solving Schrödinger Bridges via Maximum Likelihood

Francisco Vargas, Pierre Thodoroff, Austen Lamacraft, Neil D. Lawrence

Entropy, 23(9):1134

Optimal marker gene selection for cell type discrimination in single cell analyses

Bianca Dumitrascu, Soledad Villar, Dustin G. Mixon, Barbara Englehardt

Nature Communications, 12(1186):